Association of iron deficiency with atrial fibrillation recurrence after pharmacological cardioversion
نویسندگان
چکیده
Aim . This study aims to assess the association between iron deficiency (ID) and recurrences of atrial fibrillation (AF) in patients after pharmacological cardioversion with amiodarone within 12 months. Material methods The open-label, prospective, single-center included 198 non-valvular paroxysmal AF successful amiodarone. Group I 116 ID, group II — 82 normal status. primary end-point was development symptomatic months which estimated by Kaplan-Meier method. differences were considered statistically significant if p-value <0,05. Results Absolute ID found I; anemia revealed 85,3% patients. groups did not differ basic clinical demographical parameters, concomitant diseases drug therapy. Along that, older (the median 73 (64,8-79) years old 69 (63-75) old, respectively, р=0,008), their left ventricular mass larger 145 (115-176) g 132,5 (118,2-145) g, р=0,004). sinus rhythm restoration required less dose 450 (300-600) mg 1000 (600-1200) mg, р<0,001) time from start administration 7 (3-10) (9-18) hours, р<0,001). During 12-month follow-up period, 49 (42,2%) 16 (19,5%) developed (р=0,0008), hazard ratio 2,64 (95% confidence interval: 1,5-4,65) (р=0,0003). Conclusion is associated increase number
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ژورنال
عنوان ژورنال: Russian Journal of Cardiology
سال: 2023
ISSN: ['1560-4071', '2618-7620']
DOI: https://doi.org/10.15829/1560-4071-2023-5369